Professor of Anesthesiology, Neurology, Oncology, and Psychiatry
Department of Anesthesiology:
Director, Anesthesiology Clinical Research Center
Chair, Promotions Committee
Research Committee
Other Professional Activities:
Editorial Board, Pain
Editorial Board, Journal of Pain
Editorial Board, Clinical Journal of Pain
Task Force on Taxonomy, International Association for the Study of Pain
Steering Committee, Neuropathic Pain Network
Professional Advisory Board, American Chronic Pain Association
Scientific Advisory Committee, The Louise and Alan Edwards Foundation
Neuropathic Pain Management Medical Advisory Council, The Neuropathy Association
Immediate Past Chair, Neuropathic Pain Special Interest Group, International Association for the Study of Pain
Co-Chair, Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT)
Chair, International Conference on the Mechanisms and Treatment of Neuropathic Pain
Data and Safety Monitoring Board, Department of Veterans Affairs
Data and Safety Monitoring Board, National Institute of Neurological Disorders and Stroke
Special Government Employee, Center for Drug Evaluation and Research, United States Food and Drug Administration
Vice-Chair, Claim of Symptomatic Relief Working Group, Osteoarthritis Research Society International-United States Food
and Drug Administration Osteoarthritis Initiative
Research Interests:
Methodologic aspects of analgesic clinical trials.
Treatment and prevention of chronic pain.
Neuropathic pain.
Osteoarthritis.
Recent Publications
2008
Dworkin RH, Gnann JW Jr, Oaklander AL, Raja S, Schmader KE, Whitley RJ. Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia. Journal of Pain, 2008;9(suppl 1):S37-S44.
Dworkin RH, Thakur R, Griesing T, Sharma U, Young JP. Randomized clinical trials of pregabalin for neuropathic pain: methods, results, and implications. Progress in Neurotherapeutics and Neuropsychopharmacology, 2008;3:167-187.
Dworkin RH, Turk DC, Wyrwich KW, Beaton D, Cleeland CS, Farrar JT, Haythornthwaite JA, Jensen MP, Kerns RD, Ader DN, Brandenburg N, Burke LB, Cella D, Chandler J, Cowan P, Dimitrova R, Dionne R, Hertz S, Jadad AR, Katz NP, Kehlet H, Kramer LD, Manning DC, McCormick C, McDermott MP, McQuay HJ, Patel S, Porter L, Quessy S, Rappaport BA, Rauschkolb C, Revicki DA, Rothman M, Schmader KE, Stacey BR Stauffer JW, von Stein T, White RE, Witter J, Zavisic S. Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. Journal of Pain, 2008;9:105-121.
Dworkin RH, White R, O’Connor AB, Hawkins K. Health care expenditure burden of persisting herpes zoster pain. Pain Medicine, 2008;9:348-353.
Feldman EL, Cornblath DR, Porter J, Dworkin RH, Scherer S. National Institute of Neurological Disorders and Stroke (NINDS): advances in understanding and treating neuropathy, 24-25 October 2006; Bethesda, Maryland. Journal of the Peripheral Nervous System, 2008;13:1-6.
Harpaz R, Ortega-Sanchez IR, Seward JF, with the collaboration of Treanor J, Atkinson WL, Cohen JI, Dworkin RH, Gargiullo PM, Gershon AA, Glasser JW, Güris D, Haber P, Hibbs BF, Iskander JK, Katz SL, Krause PR, LaRussa PS, Levin MJ, Lieu TA, Marin ME, Neuzil KM, Nichol K, Poland GA, Rosenbaum S, Santibanez TA, Schaffner W, Schmader KE, Schmid DS, Stafford H, Strikas R, Wallace GS, Watson B, Abramson JS, Pickering LK, Allos BM, Baker C, Beck RL, Gilsdorf JR, Hull H, Lett S, Morse DL, Morita J, Stinchfield P, Sumaya CV, Womeodu RJ, Cheek J, Hachey W, Evans GS, Gellin B, Murphy L, Curlin GT, Baylor N, Temte J, Campos-Outcalt D, Powell K, Baker C, Gelzer A, Turner JC, Gall S, Tan L, Foster SL, McKinney WP, Lewin C, Naus M, Gordon S, Salisbury D, Bennett N, Duchin JS, Neumann DA, Rodriquez RS, Whitley-Williams P, Freed G, Paradiso P, Middleman AB, Araga DA. Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP). Morbidity and Mortality Weekly Report, 2008;57(RR-5):1-30.
Katz J, Finnerup NB, Dworkin RH. Clinical trial outcome in neuropathic pain: relationship to study characteristics. Neurology, 2008;70:263-272.
McGrath PJ, Walco G, Turk DC, Dworkin RH, Brown MT, Davidson K, Eccleston C, Finley GA, Goldschneider K, Haverkos L, Hertz SH, Ljungman G, Palermo T, Rappaport BA, Rhodes T, Schechter N, Scott J, Sethna N, Svensson OK, Stinson J, von Baeyer CL, Walker L, Weisman S, White RE, Zajicek A, Zeltzer L. Core outcome domains and measures for pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendations. Journal of Pain, 2008;9:771-783.
O’Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: systematic review and proposed classification. Pain, 2008;137:96-111.
Schmader KE, Dworkin RH. Natural history and treatment of herpes zoster. Journal of Pain, 2008;9(suppl 1):S3-S9.
Stacey BR, Dworkin RH, Murphy K, Sharma U, Emir B, Griesing T. Pregabalin in the treatment of refractory neuropathic pain: results of a 15-month open-label trial. Pain Medicine, 2008;9:1202-1208.
Turk DC, Dworkin RH. The initiative on methods, measurement, and pain assessment in clinical trials (IMMPACT). In Wittink HM, Carr DB, editors. Pain management: evidence, outcomes, and quality of life. Edinburgh: Elsevier, 2008:287-304.
Turk DC, Dworkin RH. Chronic pain clinical trials: IMMPACT recommendations. In Benzon HT, Rathmell JP, Wu CL, Turk DC, Argoff CE, editors. Raj’s practical management of pain, 4th edition. Philadelphia: Elsevier-Mosby, 2008:1201-1217.
Turk DC, Dworkin RH, McDermott MP, Bellamy N, Burke LB, Chandler JM, Cleeland CS, Cowan P, Dimitrova R, Farrar JT, Hertz S, Heyse JF, Iyengar S, Jadad JR, Jay GW, Jermano JA, Katz NP, Manning DC, Martin S, Max MB, McGrath P, McQuay HJ, Quessy S, Rappaport BA, Revicki DA, Rothman M, Stauffer JW, Svensson O, White RE, Witter J. Analyzing multiple endpoints in clinical trials of pain treatments: IMMPACT recommendations. Pain, 2008;139:485-493.
Turk DC, Dworkin RH, Revicki D, Harding G, Burke LB, Cella D, Cleeland CS, Cowan P, Farrar JT, Hertz S, Max MB, Rappaport BA. Identifying important outcome domains for chronic pain clinical trials: an IMMPACT survey of people with pain. Pain, 2008;137:276-285.
2009
Dworkin RH, Barbano RL, Tyring SK, Betts RF, McDermott MP, Pennella-Vaughan J, Bennett GJ, Berber E, Gnann JW, Irvine C, Kamp C, Kieburtz K, Max MB, Schmader KE. A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster. Pain, 2009;142:209-217.
Dworkin RH, Turk DC, Revicki D, Harding G, Coyne KS, Peirce-Sandner S, Bhagwat D, Everton D, Burke LB, Cowan P, Farrar JT, Hertz S, Max MB, Rappaport BA, Melzack R. Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2). Pain, 2009;144:35-42.
Foster DC, Kotok MB, Huang LS, Watts A, Oakes D, Howard FM, Stodgell CJ, Dworkin RH. Development of the Tampon Test for vulvodynia treatment outcomes research: reliability, validity, and responsiveness. Obstetrics & Gynecology, 2009;113:825-832.
Mehta LR, Dworkin RH, Schwid SR. Polyunsaturated fatty acids and their potential therapeutic role in multiple sclerosis. Nature Clinical Practice Neurology, 2009;5:82-92.
O’Connor AB, Dworkin RH. Evidence-based treatment of chronic neuropathic pain using nonopioid pharmacotherapy. Continuum Lifelong Learning in Neurology, 2009;15:69-82.
O’Connor AB, Dworkin RH. Treatment of neuropathic pain: an overview of recent guidelines. American Journal of Medicine, 2009;122(number 10A):S22-S32.
Vo T, Rice ASC, Dworkin RH. Non-steroidal anti-inflammatory drugs and neuropathic pain: how do we explain continued widespread use? Pain, 2009;143:169-171.
In press
Dworkin RH, Malone DC, Panarites CJ, Armstrong EP, Pham SV. Impact of postherpetic neuralgia and painful diabetic peripheral neuropathy on health care costs. Journal of Pain, in press.
Dworkin RH, O’Connor A, Audette J, Baron R, Gourlay G, Haanpää M, Kent J, Krane E, LeBel AA, Levy RM, Mackey S, Mayer J, Miaskowski C, Raja SN, Rice ASC, Schmader K, Stacey B, Stanos S, Treede RD, Turk DC, Walco G, Wells C. An overview and literature update of pharmacologic recommendations for the management of neuropathic pain. Mayo Clinic Proceedings, in press.
Dworkin RH, Turk DC, McDermott MP, Peirce-Sandner S, Burke LB, Cowan P, Farrar JT, Hertz S, Raja SN, Rappaport BA, Rauschkolb C, Sampaio C. Interpreting the clinical importance of group differences in chronic pain clinical trials: IMMPACT recommendations. Pain, in press.
Ellis RJ, Rosario D, Clifford D, McArthur JC, Simpson D, Alexander T, Gelman BB, Vaida F, Collier A, Marra C, Ances B, Atkinson JH, Dworkin RH, Grant I. Continued high prevalence and adverse clinical impact of HIV-associated sensory neuropathy in the era of combination antiretroviral therapy (CART): the CHARTER study. Archives of Neurology, in press.
Levin M, Gershon A, Dworkin RH, Brisson M, Stanberry L. Prevention strategies for herpes zoster and post-herpetic neuralgia. Journal of Clinical Virology, in press.
O’Connor AB, Dworkin RH. Clinical trial design for chronic pain treatments. In Stannard C, Kalso E, Ballantyne J, editors. Evidence-based chronic pain management. Oxford, UK: Blackwell Publishing, in press.
Simpson DM, McArthur JC, Dworkin RH, editors. Neuropathic pain: mechanisms and management. New York: Oxford University Press, in preparation.
Thakur R, Kent JD, Dworkin RH. Herpes zoster and postherpetic neuralgia. In Fishman S, Ballantyne JC, editors. Bonica’s management of pain, 4th edition. Oxford, UK: Blackwell Publishing, in press.
Walco G, Dworkin RH, Krane E, LeBel AA, Treede RD. Treatment considerations for children and adolescents with neuropathic pain. Mayo Clinic Proceedings, in press.
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