Dr. Papadakos Quoted in Anesthesiology News
Friday, October 2011 13:47
AddThis Social Bookmark Button
View Comments
Dr. Peter J. Papadakos was quoted in the October 2011 issue of Anesthesiology News with regard to the withdrawal of the sepsis drug, Xigris.  He was quoted as saying, "Given the marginal benefits of drotrecogin alfa, the drug probably should never have been included in sepsis guidelines established by the SCCM.  It did nothing.  Blocking one of several hundred cytokines does not make physiologic sense, but there was massive pressure to use it.  The agendas of critical-care meetings have been filled with talks about activated drotrecogin alfa for several years, which gave the drug substantial momentum in the market.  The withdrawal of drotrecogin alfa likely will not have much impact for sepsis patients, however.  We still are down to supportive therapy only, including fluids, mechanical ventilation, antibiotics and vasoactive drugs."
blog comments powered by Disqus
back to top