Dr. Dworkin

Robert H. Dworkin, Ph.D.

Professor of Anesthesiology, Neurology, Oncology, and Psychiatry
Director, Anesthesiology Clinical Research Center

Department of Anesthesiology:

Research Committee
Faculty Development and Promotions Committee

Other Professional Activities:

Editorial Board, Pain
Editorial Board, Journal of Pain
Editorial Board, Clinical Journal of Pain
Editorial Board, Current Pain and Headache Report
Editorial Board, Journal of Neuropathic Pain and Symptom Palliation
Editorial Board, Advances in Pain Management
Special Government Employee, Center for Drug Evaluation and Research, United States Food and Drug Administration
Claim of Symptomatic Relief Working Group, Osteoarthritis Research Society International-United States Food and Drug Administration Osteoarthritis Initiative
Data and Safety Monitoring Board, National Institute of Neurological Disorders and Stroke
Data and Safety Monitoring Board, Department of Veterans Affairs
Task Force on Taxonomy, International Association for the Study of Pain
Steering Committee, Neuropathic Pain Network
Scientific Advisory Committee, The Louise and Alan Edwards Foundation
Immediate Past Chair, Neuropathic Pain Special Interest Group, International Association for the Study of Pain
Co-Chair, Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT)
Chair, International Conference on the Mechanisms and Treatment of Neuropathic Pain

Areas of Special Emphasis:

Acute and chronic pain, especially neuropathic pain.

Research Interests:

Treatment and prevention of chronic pain.
Methodologic aspects of analgesic clinical trials.

Recent Publications:

2007

Barrett AM, Lucero MA, Le T, Robinson RL, Dworkin RH, Chappell AS. Epidemiology, public health burden, and treatment of diabetic peripheral neuropathic pain: a review. Pain Medicine, 2007;8(suppl 2):S50-S62.

Dworkin RH, Jensen MP, Gammaitoni AR, Olaleye DO, Galer BS. Symptom profiles differ in patients with neuropathic versus non-neuropathic pain. Journal of Pain, 2007;8:118-126. (Erratum: Journal of Pain, 2007;8:531).

Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, Betts RF, Gershon AA, Haanpää ML, McKendrick MW, Nurmikko TJ, Oaklander AL, Oxman MN, Pavan-Langston D, Petersen KL, Rowbotham MC, Schmader KE, Stacey BR, Tyring SK, van Wijck AJM, Wallace MS, Wassilew SW, Whitley RJ. Recommendations for the management of herpes zoster. Clinical Infectious Diseases, 2007;44(suppl 1):S1-S26.

Dworkin RH, O’Connor AB, Backonja M, Farrar JT, Jensen TS, Kalso EA, Loeser JD, Miaskowski C, Nurmikko TJ, Portenoy RK, Rice ASC, Stacey BR, Treede R-D, Turk DC, Wallace MS. Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain, 2007;132:237-251.

Dworkin RH, White R, O’Connor AB, Baser O, Hawkins K. Health care costs of acute and chronic pain associated with a diagnosis of herpes zoster. Journal of the American Geriatrics Society, 2007;55:1168-1175.

Hadjistavropoulos H, Herr K, Turk DC, Fine PG, Dworkin RH, Helme R, Jackson K, Parmelee PA, Rudy TE, Beattie BL, Chibnall JT, Craig KD, Ferrell B, Ferrell B, Fillingim RB, Gagliese L, Gallagher R, Gibson SJ, Harrison L, Katz B, Keefe FJ, Lieber SJ, Lussier D, Schmader KE, Tait RC, Weiner DK, Williams J. An interdisciplinary expert consensus statement on assessment of pain in older persons. Clinical Journal of Pain, 2007;23(suppl):S1-S43.

Jensen MP, Chodroff MJ, Dworkin RH. The impact of neuropathic pain on health-related quality of life: review and implications. Neurology, 2007;68:1178-1182.

2008

Dworkin RH, Gnann JW Jr, Oaklander AL, Raja S, Schmader KE, Whitley RJ. Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia. Journal of Pain, 2008;9(suppl 1):S37-S44.

Dworkin RH, Thakur R, Griesing T, Sharma U, Young JP. Randomized clinical trials of pregabalin for neuropathic pain: methods, results, and implications. Progress in Neurotherapeutics and Neuropsychopharmacology, 2008;3:167-187.

Dworkin RH, Turk DC, Wyrwich KW, Beaton D, Cleeland CS, Farrar JT, Haythornthwaite JA, Jensen MP, Kerns RD, Ader DN, Brandenburg N, Burke LB, Cella D, Chandler J, Cowan P, Dimitrova R, Dionne R, Hertz S, Jadad AR, Katz NP, Kehlet H, Kramer LD, Manning DC, McCormick C, McDermott MP, McQuay HJ, Patel S, Porter L, Quessy S, Rappaport BA, Rauschkolb C, Revicki DA, Rothman M, Schmader KE, Stacey BR Stauffer JW, von Stein T, White RE, Witter J, Zavisic S. Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. Journal of Pain, 2008;9:105-121.

Dworkin RH, White R, O’Connor AB, Hawkins K. Health care expenditure burden of persisting herpes zoster pain. Pain Medicine, 2008;9:348-353.

Feldman EL, Cornblath DR, Porter J, Dworkin RH, Scherer S. National Institute of Neurological Disorders and Stroke (NINDS): advances in understanding and treating neuropathy, 24-25 October 2006; Bethesda, Maryland. Journal of the Peripheral Nervous System, 2008;13:1-6.

Katz J, Finnerup NB, Dworkin RH. Clinical trial outcome in neuropathic pain: relationship to study characteristics. Neurology, 2008;70:263-272.

McGrath PJ, Walco G, Turk DC, Dworkin RH, Brown MT, Davidson K, Eccleston C, Finley GA, Goldschneider K, Haverkos L, Hertz SH, Ljungman G, Palermo T, Rappaport BA, Rhodes T, Schechter N, Scott J, Sethna N, Svensson OK, Stinson J, von Baeyer CL, Walker L, Weisman S, White RE, Zajicek A, Zeltzer L. Core outcome domains and measures for pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendations. Journal of Pain, 2008;9:771-783.

O’Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: systematic review and proposed classification. Pain, 2008;137:96-111.

Schmader KE, Dworkin RH. Natural history and treatment of herpes zoster. Journal of Pain, 2008;9(suppl 1):S3-S9.

Turk DC, Dworkin RH. The initiative on methods, measurement, and pain assessment in clinical trials (IMMPACT). In Wittink HM, Carr DB (eds), Pain management: evidence, outcomes, and quality of life. Edinburgh: Elsevier, 2008:287-304.

Turk DC, Dworkin RH. Chronic pain clinical trials: IMMPACT recommendations. In Benzon HT, Rathmell JP, Wu CL, Turk DC, Argoff CE (eds), Raj’s practical management of pain, 4th edition. Philadelphia: Elsevier-Mosby, 2008:1201-1217.

Turk DC, Dworkin RH, McDermott MP, Bellamy N, Burke LB, Chandler JM, Cleeland CS, Cowan P, Dimitrova R, Farrar JT, Hertz S, Heyse JF, Iyengar S, Jadad JR, Jay GW, Jermano JA, Katz NP, Manning DC, Martin S, Max MB, McGrath P, McQuay HJ, Quessy S, Rappaport BA, Revicki DA, Rothman M, Stauffer JW, Svensson O, White RE, Witter J. Analyzing multiple endpoints in clinical trials of pain treatments: IMMPACT recommendations. Pain, 2008;139:485-493.

Turk DC, Dworkin RH, Revicki D, Harding G, Burke LB, Cella D, Cleeland CS, Cowan P, Farrar JT, Hertz S, Max MB, Rappaport BA. Identifying important outcome domains for chronic pain clinical trials: an IMMPACT survey of people with pain. Pain, 2008;137:276–285.

2009 and in press

Mehta LR, Dworkin RH, Schwid SR. Polyunsaturated fatty acids and their potential therapeutic role in multiple sclerosis. Nature Clinical Practice Neurology, 2009;5:82-92.

Dworkin RH, Barbano RL, Tyring SK, Betts RF, McDermott MP, Pennella-Vaughan J, Bennett GJ, Berber E, Gnann JW, Irvine C, Kamp C, Kieburtz K, Max MB, Schmader KE. A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster. Pain, in press.

Dworkin RH, Turk DC, Revicki D, Harding G, Coyne KS, Peirce-Sandner S, Bhagwat D, Everton D, Burke LB, Cowan P, Farrar JT, Hertz S, Max MB, Rappaport BA, Melzack R. Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2). Pain, in press.

O’Connor AB, Dworkin RH. Treatment of neuropathic pain: an overview of recent guidelines. American Journal of Medicine, in press.

O’Connor AB, Dworkin RH. Clinical trial design for chronic pain treatments. In Stannard C, Kalso EA, Ballantyne JC (eds), Evidence-based chronic pain management. Oxford, UK: Blackwell Publishing, in press.

Stacey BR, Dworkin RH, Sharma U, Emir B, Griesing T, Murphy K. The effectiveness of pregabalin in patients with treatment-refractory neuropathic pain. Pain Medicine, in press.

Thakur R, Kent JD, Dworkin RH. Herpes zoster and postherpetic neuralgia. In Fishman S, Ballantyne JC (eds), Bonica’s management of pain, 4th edition. Oxford, UK: Blackwell Publishing, in press.

Simpson DM, McArthur JC, Dworkin RH, eds. Neuropathic pain: mechanisms and management. New York: Oxford University Press, in preparation.

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